Cortisol
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- A group of hormone called glucocorticoids
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- 8 a.m-10 a.m: 5-23 µg/dl
- 4 p.m-6 p.m: 3-13 µg/dl
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- To diagnose Cushing's Syndrome, Cushing's disease, and primary and secondary adrenal insufficiency
- To distinguish between primary and secondary adrenal insufficiency
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- Stress
- Acute illness
- Surgery
- Trauma
- Pregnancy
- Anxiety
- Exogenous estrogen
- Starvation
- Anorexia nervosa
- Alcoholism
- Renal failure
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- Addison's disease
- Hypophysectomy
- Postpartum pituitary necrosis
- Pituitary destruction
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- Noncompliance with dietary or activity restrictions
- With RIA: Androgen, Estrogen, Phenytoin, Hepatic dysfunction, renal failure
- With competitive protein binding assay: Prednisolone, 6-alpha-methylprednisolone
- With fluorometric assays: Jaundice, renal failure, medications
- With high-performance liquid chromatography: Prednisone, prednisolone
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