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Thursday, November 20, 2008
  
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   Antiglobulin direct indirect (Coombs direct indirect)


  • Blood

  • Negative

  • To detect antibodies on the erythrocytes and in the serum
  • Used in the diagnosis and treatment of maternal-fetal blood incompatibility
  • To diagnose hemolytic anemia
  • In evaluation of a blood tranfusion reaction caused by incompatibility

  • Direct antiglobulin test
    1. Autoimmune hemolytic anemia
    2. Hemolytic transfusion reaction
    3. Hemolytic disease of the newborn
    4. Sensitivity to particulr medications (methyldopa, levodopa)
  • Indirect antiglobulin test
    1. Maternal-fetal blood incompatability
    2. Autoimmune hemolytic anemia
    3. Sensitivity to particular medications

  • Hemolysis
  • Inadequate identification of the specimen

 
 


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