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Acute Poststreptococcal Glomerulonephritis

APSGN

This is the most common form of glomerulonephritis, a disorder marked by inflammation of the kidneys' glomeruli.
  • Dark brown urine
  • Periorbital swelling
  • Shortness of Breath
  • Rapid breathing
  • Pallor
  • High blood pressure
  • Diarrhea
  • Decreased urine output
  • Seizures
  • Streptococcal infection (nephritogenic strain)
  • Pharyngitis -- M type 12
  • Skin Infection: M type 49
    •  
    • Streptococcal infection evidence
    • Laboratory tests:
      1. Manual blood count shows anemia
      2. Elevated blood urea nitrogen (BUN) level
      3. Elevated creatinine (Cr) level
      4. Streptococcus serologic tests (ASO, antihyaluronidase, antideoxyribonuclease) level
      5. Decreased complement 3 level
        Microscopic urine examine shows protein, RBC, WBC in urine
     
    • Penicillin for 10 days
    • For kidney failure:
      1. Restrict fluid
      2. Maintain calories
      3. Correction of electrolyte disturbance
    • For high blood pressure:
      1. Hospitalization
      2. Diazoxide for pulmonary edema
    Your child needs to be hospitalized if he/she has high blood pressure.
  • Acute renal failure
  • Hypertensive encephalopathy
  • Heart failure
  • Lupus nephritis
  • Membranoproliferative glomerulonephritis (MPGN)
  • Nephritis due to bacterial endocarditis
  • Shunt nephritis
    • Ninety-five percent of patients recover completely.
     


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